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[Bone mass accrual during infancy]

Hiroyuki Tanaka1

  • 1Department of pediatrics, Okayama Saiseikai General Hospital, Japan.

Clinical Calcium
|September 2, 2011
PubMed

Insights

Infant bone mass is crucial for lifelong skeletal health and osteoporosis prevention. Key factors influencing bone accrual include third-trimester growth, nutrition (vitamin D, calcium), and endocrine factors like estrogen.

Area of Science:

  • Pediatrics
  • Endocrinology
  • Nutrition Science

Context:

  • Infantile bone mass is a significant predictor of adult bone density.
  • Low bone mass in infancy is a potential risk factor for developing osteoporosis later in life.
  • Bone mass accrual during infancy is influenced by perinatal conditions, nutrition, and endocrine factors.

Purpose:

  • To highlight the critical role of infant growth, particularly during the third trimester of pregnancy, in determining long-term bone health.
  • To emphasize the importance of key nutritional factors, vitamin D and calcium, for bone mass development in infants.
  • To explore the influence of endocrine factors, including estrogen, on infant bone health.

Summary:

  • Infant bone mass is closely linked to adult bone mass, with low infantile bone mass being a risk factor for osteoporosis.
  • Third-trimester fetal growth is a critical determinant of lifelong bone health.
  • Adequate intake of vitamin D and calcium, alongside hormonal influences like estrogen, plays a vital role in infant bone accrual.

Impact:

  • Understanding these factors can inform strategies for optimizing infant nutrition and growth to promote peak bone mass.
  • Early identification and intervention for factors affecting infant bone development may reduce the future burden of osteoporosis.
  • This research underscores the importance of prenatal and early postnatal care for establishing a foundation for skeletal health throughout life.

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