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Mitral valve repair in a patient with myelodysplastic syndrome

Tadashi Omoto1, Masanori Hirota, Noboru Ishikawa

  • 1Department of Surgery, Division of Thoracic and Cardiovascular Surgery, Showa University, Hatanodai 1-5-8, Shinagawa-ku, Tokyo, Japan. tomoto@med.showa-u.ac.jp

Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
|September 2, 2011
PubMed

Insights

Mitral valve repair in patients with myelodysplastic syndrome (MDS) is feasible. This case study shows successful mitral valve repair in an MDS patient, offering a potential alternative to valve replacement.

Area of Science:

  • Cardiovascular Surgery
  • Hematology

Background:

  • Open heart surgery in myelodysplastic syndrome (MDS) patients carries high risks of bleeding and infection.
  • Rheumatic heart disease can lead to complex mitral valve pathologies, including severe mitral regurgitation and stenosis.

Observation:

  • A 67-year-old female patient with rheumatic heart disease and myelodysplastic syndrome (MDS) presented with severe mitral regurgitation and stenosis.
  • The patient underwent a complex mitral valve (MV) repair procedure involving commissurotomy, autologous pericardial augmentation, and artificial chordae implantation.

Findings:

  • Postoperative echocardiography confirmed a significant increase in the MV orifice and only trivial mitral regurgitation.
  • Two-year follow-up revealed normal sinus rhythm and stable mitral valve function without deterioration.

Implications:

  • Mitral valve repair, despite challenges in rheumatic heart disease, may be a viable and preferred option for select MDS patients.
  • This approach could potentially improve outcomes and reduce complications in MDS patients requiring cardiac surgery.

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