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Long-term survival of octogenarian patients submitted to isolated coronary artery bypass graft surgery
Fernando Pivatto Júnior1, Felipe H Valle, Edemar M C Pereira
1Cardiology Institute of Rio Grande do Sul / University Foundation of Cardiology (IC/FUC).
Insights
Long-term survival after coronary artery bypass graft (CABG) surgery in octogenarians is significant, with a 5-year survival rate of 65.2%. Hospital mortality for this elderly group has decreased over time.
Area of Science:
- Cardiovascular Surgery
- Geriatric Medicine
- Outcomes Research
Background:
- An increasing number of octogenarians are undergoing coronary artery bypass graft (CABG) surgery.
- While short-term outcomes are well-documented, long-term data for this age group remain limited.
- This study addresses the need for national reports on long-term outcomes in elderly CABG patients.
Purpose of the Study:
- To evaluate hospital mortality and long-term survival rates.
- Focus on patients aged over 80 years undergoing isolated CABG.
- Provide insights into outcomes for this specific demographic.
Main Methods:
- Retrospective cohort study of 142 patients aged > 80 years.
- Data collected from a Brazilian reference center between 1996 and 2007.
- Kaplan-Meier method used for survival analysis with a median follow-up of 4.0 years.
Main Results:
- Overall hospital mortality was 14.8%, showing a decreasing trend over the study period.
- Mean survival reached 6.5 years.
- Survival rates at 1, 3, and 5 years were 79.4%, 73.4%, and 65.2%, respectively.
Conclusions:
- Long-term survival outcomes for octogenarian CABG patients are comparable to international reports.
- A 5-year survival rate of 65.2% indicates the viability of CABG in this population.
- The study highlights a reduction in hospital mortality over time, suggesting improved surgical management.
Introduction:
An increasing number of octogenarian patients is undergoing coronary artery bypass graft surgery (CABG). The short-term results of this procedure have been broadly studied, but there are few national reports on long-term outcomes.
Objectives:
To describe hospital mortality and long-term survival of patients aged > 80 years undergoing isolated CABG.
Methods:
Retrospective cohort study with 142 consecutive patients aged > 80 years undergoing isolated CABG in the period between January/1996 and December/2007 in a Brazilian reference center. Mean age (± SD) was 82.3 ± 2.1 years, and 56.3% were male. The prevalence of hypertension was 73.2%, of previous myocardial infarction 30.3%, of diabetes 26.8%, and of renal dysfunction (creatinine ³ 2.0 mg/ml) was 4.9%. The median follow-up was 4.0 years, with a loss of 11.6% of patients. Survival analysis was performed by the Kaplan-Meier method.
Results:
Overall hospital mortality was 14.8% (95% CI: 8.8 to 20.8), with a reduction of this rate during the study period (1996-1999: 25.9%, 2000-2003: 15.8%, and 2004-2007: 8.6%). Mean survival was 6.5 years (95% CI: 5.5 to 7.5), and the survival rate at 1, 3 and 5 years was 79.4, 73.4 and 65.2%, respectively.
Conclusion:
Results are in agreement with international reports. Mean survival was 6.5 years and the survival rate at 5 years was 65.2%.
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