[Complex ultrasound examination children with persisting hyperplastic primary vitreous]

Area of Science:

• Ophthalmology
• Pediatric Medicine
• Medical Imaging

Background:

• Unilateral congenital cataract (UCC) and persisting hyperplastic primary vitreous syndrome (PHPVS) are significant causes of pediatric vision impairment.
• Accurate assessment of PHPVS is crucial for determining surgical intervention.
• Current diagnostic methods require refinement for precise evaluation of disease severity.

Purpose of the Study:

• To utilize complex ultrasound examination in children with UCC and PHPVS.
• To identify indications and contraindications for surgical treatment.
• To correlate ultrasound findings with the severity of PHPVS.

Main Methods:

• 108 children with UCC and PHPVS underwent complex ultrasound examinations.
• Color Doppler and energetic mapping assessed vascularity and linear blood flow velocity (LBFV) in fibrovascular bands and retrolenticular membranes (RLM).
• Echodensitometry measured the echographic density of fibrovascular bands and RLM.

Main Results:

• A correlation was observed between PHPVS severity and fibrovascular band diameter.
• LBFV within the fibrovascular band vessels showed a correlation with PHPVS severity.
• Echographic density and thickness of the fibrovascular band and RLM were also correlated with PHPVS severity.

Conclusions:

• Complex ultrasound examination provides valuable quantitative data for assessing PHPVS.
• Ultrasound parameters like LBFV, echodensity, and thickness can help stage PHPVS severity.
• These findings can guide surgical decision-making in pediatric ophthalmology.