Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
Spinal Cord: Gross Anatomy01:15

Spinal Cord: Gross Anatomy

The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
The Spinal Cord01:54

The Spinal Cord

The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
Spinal Cord: Cross-sectional Anatomy01:16

Spinal Cord: Cross-sectional Anatomy

The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Serum Metabolomic Signature of Gliomas in an Indian Cohort: Identification of Grade-Specific Alterations and Potential Biomarkers.

Neurology India·2026
Same author

Economic Evaluation of Surgery Alone versus Surgery Plus Adjuvant Therapy for Glioblastomas in India.

Neurology India·2025
Same author

Association of Cerebellar Peduncle Morphometry with Hypertrophic Olivary Degeneration: A Pilot Case-Control Study.

AJNR. American journal of neuroradiology·2025
Same author

Three cases of pituicytoma with a review of the literature and insight into a rare variant of ependymal pituicytoma.

Clinical neuropathology·2025
Same author

Giant brain Stone: Calcifying pseudoneoplasm of the neuraxis (CAPNON).

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2024
Same author

Radiation-induced Moyamoya syndrome-missed diagnosis with a fatal outcome in a recurrent craniopharyngioma.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2024

Related Experiment Video

Updated: May 29, 2026

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review
04:33

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review

Published on: November 8, 2024

A sacral arachnoid cyst causing holocord syringomyelia.

Sumit Thakar1, Narayanam Anantha Sai Kiran, Alangar S Hegde

  • 1Department of Neurosurgery, Sri Sathya Sai Institute of Higher Medical Sciences, Whitefield, Bangalore, India. sumit.thakar@gmail.com

Journal of Neurosurgery. Pediatrics
|September 3, 2011
PubMed
Summary

Sacral extradural arachnoid cysts are rare and usually asymptomatic. This case highlights a sacral extradural arachnoid cyst causing holocord syringomyelia, a previously undescribed presentation.

Related Experiment Videos

Last Updated: May 29, 2026

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review
04:33

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review

Published on: November 8, 2024

Area of Science:

  • Neurosurgery
  • Spinal Imaging
  • Neurology

Background:

  • Spinal extradural arachnoid cysts (ACs) are uncommon, with a rare predilection for the sacrum.
  • Most sacral ACs are asymptomatic; symptomatic cases typically present with low back pain, radiculopathy, or sphincteric dysfunction.

Observation:

  • A 15-year-old male presented with fluctuating spastic paraparesis and dissociated sensory loss.
  • MR imaging revealed a sacral extradural AC (S-2 to S-4) and a holocord syrinx.

Findings:

  • The patient underwent surgical intervention including laminectomy, cyst fenestration, and partial excision.
  • Post-operatively, motor and sensory deficits resolved, and MR imaging showed complete syrinx resolution.
  • The sacral AC also resolved post-operatively, with no dural communication identified.

Implications:

  • This is the first reported case of a sacral extradural AC causing holocord syringomyelia.
  • The findings challenge conventional theories of syrinx formation, necessitating new hypotheses.
  • Highlights the importance of considering rare spinal pathologies in complex neurological presentations.