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Published on: January 2, 2026
Robot-assisted partial nephrectomy for sporadic ipsilateral multifocal renal tumours
Humberto Laydner1, Riccardo Autorino, Gregory Spana
1Center for Laparoscopic and Robotic Surgery, Glickman Urological and Kidney Institute Cleveland Clinic Foundation, OH, USA.
BJU International
|September 3, 2011
Summary
Robot-assisted partial nephrectomy is a safe and feasible option for treating multiple kidney tumors on the same side. This minimally invasive approach allows for effective removal of sporadic ipsilateral renal masses with good outcomes.
Area of Science:
- Urology
- Minimally Invasive Surgery
- Oncology
Background:
- Multiple ipsilateral renal tumors present a surgical challenge.
- Partial nephrectomy is the gold standard for preserving renal function.
Purpose of the Study:
- To evaluate the short-term outcomes of robot-assisted partial nephrectomy (RAPN) for sporadic multiple ipsilateral renal tumors.
- To assess the feasibility and safety of RAPN in this specific patient group.
Main Methods:
- Retrospective review of eight patients undergoing nine RAPNs for multiple ipsilateral renal masses over three years.
- Evaluation of PADUA and R.E.N.A.L. nephrometry scores, operative details, complications (Clavien classification), and renal function.
- Analysis of histopathological findings.
Main Results:
- Nineteen tumors were resected in nine procedures with no intraoperative complications or need for blood transfusion.
- Mean operative time was 200 minutes; mean tumor size was 2.2 cm.
- Mean warm ischemia time was 21 minutes (for off-clamp resections); mean decrease in glomerular filtration rate was 4% with 14-month follow-up.
- Most resected tumors (16/19) were malignant, predominantly papillary type, Fuhrman grade II.
Conclusions:
- Robot-assisted partial nephrectomy is a safe and feasible surgical option for managing sporadic ipsilateral multifocal renal tumors.
- Off-clamp resection of multiple renal tumors can be safely performed in select cases using robotic assistance.

