Synthesis and antibacterial activity of aromatic and heteroaromatic amino alcohols
Camila G de Almeida1, Samira G Reis, Angelina M de Almeida
1Departamento de Qumica, ICE, Universidade Federal de Juiz de Fora, 36036-330 Juiz de Fora, MG, Brazil.
Abstract:
Two series of aromatic and heteroaromatic amino alcohols were synthesized from alcohols and aldehydes and evaluated for their antibacterial activities. All the octylated compounds displayed a better activity against the four bacteria tested when evaluated by the agar diffusion method and were selected for the evaluation of minimal inhibitory concentration. The best results were obtained for p-octyloxybenzyl derivatives against Staphylococcus epidermidis (minimal inhibitory concentrations = 32 μm).
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