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Related Experiment Video

Updated: May 29, 2026

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes
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Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes

Published on: March 22, 2022

Canine reference intervals for the Sysmex XT-2000iV hematology analyzer.

Nathalie Bourgès-Abella1, Anne Geffré, Didier Concordet

  • 1Department of Small Animal Clinical Sciences, Ecole Nationale Vétérinaire, Toulouse, France. n.bourges-abella@envt.fr

Veterinary Clinical Pathology
|September 3, 2011
PubMed
Summary

This study established canine hematologic reference intervals using the Sysmex XT-2000iV analyzer. Results provide crucial data for veterinary diagnostics, accounting for age and breed variations in platelet and white blood cell counts.

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Area of Science:

  • Veterinary Clinical Pathology
  • Hematology
  • Comparative Pathology

Background:

  • The Sysmex XT-2000iV hematology analyzer is widely adopted in veterinary labs.
  • Instrument-specific canine reference intervals are currently unavailable, hindering accurate diagnostics.

Purpose of the Study:

  • To establish canine hematologic reference intervals using the Sysmex XT-2000iV.
  • To adhere to International Federation of Clinical Chemistry and Clinical and Laboratory Standards Institute guidelines.

Main Methods:

  • Analyzed blood samples from 132 healthy purebred dogs representing prevalent French breeds.
  • Established reference intervals using the nonparametric method and assessed platelet aggregates.
  • Compared impedance and optical methods for platelet and RBC counts, and evaluated sex and age effects.

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Published on: September 12, 2016

Related Experiment Videos

Last Updated: May 29, 2026

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes
05:58

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes

Published on: March 22, 2022

Measuring Granulocyte and Monocyte Phagocytosis and Oxidative Burst Activity in Human Blood
11:29

Measuring Granulocyte and Monocyte Phagocytosis and Oxidative Burst Activity in Human Blood

Published on: September 12, 2016

Main Results:

  • Excellent correlation between impedance and optical methods for RBC and PLT counts, but significant differences were noted.
  • Age significantly impacted white blood cell, lymphocyte, and neutrophil counts.
  • Breed-specific differences in eosinophil counts were observed, and platelet aggregates affected impedance-based platelet counts.

Conclusions:

  • Established reliable hematologic reference intervals for dogs under controlled conditions.
  • Findings align with international recommendations for well-characterized canine populations.
  • Provides essential data for accurate veterinary clinical pathology diagnostics.