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Updated: May 29, 2026

Simple Generation of a High Yield Culture of Induced Neurons from Human Adult Skin Fibroblasts
Published on: February 5, 2018
Converting human skin cells to neurons: a new tool to study and treat brain disorders?
1Molecular Neurobiology Laboratory, Department of Psychiatry, Program in Neuroscience and Harvard Stem Cell Institute, McLean Hospital/Harvard Medical School, Belmont, MA 02478, USA. kskim@mclean.harvard.edu
Abstract:
Recent publications in Cell Stem Cell (Son et al., 2011; Ambasudhan et al., 2011), PNAS (Pfisterer et al., 2011), and Nature (Caiazzo et al., 2011; Pang et al., 2011; Yoo et al., 2011) report that functional neurons can be directly generated from human fibroblast cells without going through the pluripotent state.
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