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Updated: May 29, 2026

In vivo Imaging of Transgenic Leishmania Parasites in a Live Host
Published on: July 27, 2010
[Unsuspected visceral leishmaniasis infiltrating a squamous cell carcinoma]
M Armengot-Carbó1, R Carmena-Ramón, B Rodrigo-Nicolás
1Servicio de Dermatología, Hospital Arnau de Vilanova, Valencia, España. miquelarmengot@gmail.com
Abstract:
Amastigotes of the genus Leishmania have been observed in biopsies of apparently unrelated lesions in patients with AIDS and visceral leishmaniasis. We describe the case of a 40-year-old man with human immunodeficiency virus infection and severe immunodepression in whom the presence of the parasite was detected as an incidental finding on histological study of a perianal squamous cell carcinoma. This finding led to the diagnosis and subsequent treatment of previously unsuspected visceral leishmaniasis. In a review of the literature we have found no previous examples of this association.
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