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Related Concept Videos

Spinal Cord: Cross-sectional Anatomy01:16

Spinal Cord: Cross-sectional Anatomy

The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
Nondisjunction01:29

Nondisjunction

During meiosis, chromosomes occasionally separate improperly. This occurs due to failure of homologous chromosome separation during meiosis I or failed sister chromatid separation during meiosis II. In some species, notably plants, nondisjunction can result in an organism with an entire additional set of chromosomes, which is called polyploidy. In humans, nondisjunction can occur during male or female gametogenesis and the resulting gametes possess one too many or one too few chromosomes.

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Updated: May 29, 2026

Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats
08:46

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Published on: March 24, 2020

Mixed split cord malformation: are we missing something?

Pravin Salunke1, Priyamvadha Kovai, Vinod Malik

  • 1Neurosurgery, PGIMER, Chandigarh 160012, India. drpravin salunke@yahoo.co.uk

Clinical Neurology and Neurosurgery
|September 3, 2011
PubMed
Summary
This summary is machine-generated.

Split cord malformation classification is challenged by two cases exhibiting features of both Type I and II. This suggests an overlap exists between these distinct types, contrary to the unified theory.

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Understanding Cerebellar Pattern Formation
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Published on: November 1, 2007

Area of Science:

  • Developmental biology
  • Neuroscience
  • Pediatric neurology

Background:

  • The current classification of split cord malformation (SCM) categorizes it into Type I and Type II based on embryogenesis.
  • This classification posits distinct features for each type, with no overlap.
  • The unified theory of SCM classification relies on the median septum and dural tube state.

Observation:

  • Two pediatric patients with split cord malformation presented with combined features of Type I and Type II.
  • Both patients exhibited a partial bony spur within a single dural sac.

Findings:

  • The observed cases demonstrate an overlap between Type I and Type II split cord malformation.
  • The findings challenge the strict dichotomy proposed by the unified theory of SCM classification.

Implications:

  • This study suggests the existing classification of split cord malformation may require revision.
  • Further research is needed to understand the embryological mechanisms leading to overlapping SCM types.
  • The role of the meninx primitiva in median bony septum formation warrants further investigation.