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Updated: May 29, 2026

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High-Definition Transcranial Direct Current Stimulation During Sleep
Published on: December 5, 2025
Transcranial direct current stimulation in refractory continuous spikes and waves during slow sleep: a controlled
Edina T Varga1, Daniella Terney, Mary D Atkins
1Department of Neurophysiology, Danish Epilepsy Centre, Dianalund, Denmark.
Epilepsy Research
|September 3, 2011
Abstract:
Cathodal transcranial direct current stimulation (tDCS) decreases cortical excitability. The purpose of the study was to investigate whether cathodal tDCS could interrupt the continuous epileptiform activity. Five patients with focal, refractory continuous spikes and waves during slow sleep were recruited. Cathodal tDCS and sham stimulation were applied to the epileptic focus, before sleep (1 mA; 20 min). Cathodal tDCS did not reduce the spike-index in any of the patients.

