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Updated: May 12, 2026

In Vivo Modeling of the Morbid Human Genome using Danio rerio
Published on: August 24, 2013
Comment on "Additive genetic breeding values correlate with the load of partially deleterious mutations"
1Institute of Evolutionary Biology and Environmental Studies, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland. erik.postma@ieu.uzh.ch
Abstract:
Tomkins et al. (Reports, 14 May 2010, p. 892) reported a strong negative correlation between breeding values and mutational load in cow-pea weevils. Here, I show that this result can be attributed to a statistical artifact. By testing the observed correlation against an incorrect null hypothesis, they find a negative correlation where one does not exist.
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