Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Uniplanar aquatic exercise quantified with inertial sensors and pose estimation.

Scientific reports·2025
Same author

Changes in femoral neck bone mineral density and structural strength during a 12-month multicomponent exercise intervention among older adults - Does accelerometer-measured physical activity matter?

Bone·2023
Same author

European consensus statement on expert colposcopy.

European journal of obstetrics, gynecology, and reproductive biology·2023
Same author

Effects of a Multi-component, Resistance-Based Exercise Program Combined with Additional Lean Red Meat on Health-Related Quality of Life in Older Adults: Secondary Analysis of a 6-Month Randomized Controlled Trial.

The journal of nutrition, health & aging·2023
Same author

Cardiorespiratory fitness is associated with sickness absence and work ability.

Occupational medicine (Oxford, England)·2022
Same author

Dietary Saturated Fat and Bone Health in Young Adults: The Young Finns Cohort.

Calcified tissue international·2022

Related Experiment Video

Updated: May 29, 2026

Longitudinal Micro-Computed Tomography Image Analysis for User-Defined Region of Interest in Critical-Sized Bone Defects
08:39

Longitudinal Micro-Computed Tomography Image Analysis for User-Defined Region of Interest in Critical-Sized Bone Defects

Published on: June 24, 2025

An open source approach for regional cortical bone mineral density analysis.

T Rantalainen1, R Nikander, A Heinonen

  • 1Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, Melbourne, VIC 3125, Australia. timo.rantalainen@deakin.edu.au

Journal of Musculoskeletal & Neuronal Interactions
|September 3, 2011
PubMed
Summary

Assessing cortical bone density distribution with peripheral quantitative computed tomography (pQCT) reveals age-related differences missed by average measurements. This method highlights regional variations crucial for understanding bone fragility.

More Related Videos

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

A Sectioning, Coring, and Image Processing Guide for High-Throughput Cortical Bone Sample Procurement and Analysis for Synchrotron Micro-CT
07:10

A Sectioning, Coring, and Image Processing Guide for High-Throughput Cortical Bone Sample Procurement and Analysis for Synchrotron Micro-CT

Published on: June 12, 2020

Related Experiment Videos

Last Updated: May 29, 2026

Longitudinal Micro-Computed Tomography Image Analysis for User-Defined Region of Interest in Critical-Sized Bone Defects
08:39

Longitudinal Micro-Computed Tomography Image Analysis for User-Defined Region of Interest in Critical-Sized Bone Defects

Published on: June 24, 2025

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

A Sectioning, Coring, and Image Processing Guide for High-Throughput Cortical Bone Sample Procurement and Analysis for Synchrotron Micro-CT
07:10

A Sectioning, Coring, and Image Processing Guide for High-Throughput Cortical Bone Sample Procurement and Analysis for Synchrotron Micro-CT

Published on: June 12, 2020

Area of Science:

  • Bone biology and biomechanics
  • Medical imaging and diagnostics
  • Gerontology and aging research

Background:

  • Cortical porosity, especially at the endocortical surface, is a key factor in bone fragility.
  • Understanding regional variations in cortical bone density is critical for assessing skeletal health.

Purpose of the Study:

  • To demonstrate a method for analyzing cortical volumetric bone mineral density (vBMD) distribution from peripheral quantitative computed tomography (pQCT) images.
  • To highlight the clinical significance of assessing regional cortical bone density distribution.

Main Methods:

  • Peripheral quantitative computed tomography (pQCT) was used to compare mid-tibial cortical volumetric BMD distribution in young and elderly men.
  • A custom open-source analysis tool divided the cortex into concentric divisions and sectors for detailed radial and polar vBMD analysis.

Main Results:

  • Mean vBMD did not significantly differ between young and elderly men.
  • A significant interaction between age group and radial division was observed for radial cortical vBMD, indicating regional density differences.

Conclusions:

  • The developed pQCT analysis method effectively detects regional cortical bone density variations between age groups.
  • This approach identifies age-related differences in cortical density that average vBMD measurements would overlook.