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[The heart and diabetes mellitus]
I Lerman Garber1, M Ahumada Ayala, C Posadas Romero
1Departamento de Endocrinología, Instituto Nacional de Cardiología Ignacio Chávez, México, D.E.
Archivos Del Instituto De Cardiologia De Mexico
|January 1, 1990
Summary
Diabetic patients experience more frequent and rapid atherosclerosis due to intrinsic factors. Early detection of cardiovascular changes in these patients is crucial for risk reduction and improved outcomes.
Area of Science:
- Cardiology
- Endocrinology
- Diabetology
Context:
- Diabetes mellitus significantly accelerates atherosclerosis, affecting both genders early and rapidly.
- This accelerated process is attributed to intrinsic diabetic factors beyond traditional risk factors.
- Coronary heart disease (CHD) prevalence and post-event mortality are markedly higher in diabetic individuals.
Purpose:
- To elucidate the unique atherosclerotic burden in diabetic patients.
- To explore the intrinsic mechanisms driving accelerated cardiovascular disease in diabetes.
- To highlight the increased morbidity and mortality associated with cardiovascular events in diabetes.
Summary:
- Diabetic patients exhibit accelerated atherosclerosis, independent of other risk factors, linked to hyperinsulinemia, lipid and coagulation disorders, hyperglycemia, and microangiopathy.
- Coronary heart disease is more prevalent in diabetics, with double the morbimortality post-myocardial infarction or revascularization.
- Cardiovascular denervation syndrome and early, subclinical cardiovascular changes in asymptomatic diabetics impact prognosis.
Impact:
- Understanding diabetes-intrinsic atherogenesis can guide targeted preventive strategies.
- Early detection of cardiovascular changes in diabetics via non-invasive tests can mitigate risks.
- This research underscores the critical need for proactive cardiovascular management in diabetic populations.