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Published on: August 15, 2022

A suspected case of transfusion-related acute lung injury

Lulu Sherif1, J Srikantu, Prithi Jain

  • 1Department of Anaesthesiology, Father Muller Medical College, Mangalore, Karnataka, India.

Lung India : Official Organ of Indian Chest Society
|September 3, 2011
PubMed

Transfusion-related acute lung injury (TRALI) is a rare but serious complication of blood transfusion. We present a suspected case of TRALI in a 39-year-old female patient who underwent total abdominal hysterectomy under uneventful general anesthesia. The patient developed acute desaturation due to noncardiogenic pulmonary edema while receiving compatible blood transfusion on the second postoperative day. As her symptoms were refractory to supportive treatment, she was mechanically ventilated for 3 days and successfully extubated on the fourth day. By exclusion, a clinical diagnosis of TRALI was made. The treatment for TRALI requires discontinuing transfusion and giving respiratory and cardiovascular support. Most cases show clinical improvement in first few hours and resolve completely within 96 h.

Keywords:
Acute lung injuryantibodiesblood transfusionleukocytesmechanical ventilation noncardiogenic pulmonary edematransfusion-related acute lung injury

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