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Related Experiment Video

Updated: May 29, 2026

Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation

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Published on: June 5, 2012

Schistosoma hematobium-associated glomerulopathy.

S M Seck¹, M L Sarr, M C Dial

¹Department of Nephrology, University Hospital Aristide Le Dantec, Dakar, Senegal.

Indian Journal of Nephrology

|September 3, 2011

Summary

Schistosomiasis, a tropical disease, can cause rare kidney complications. This case highlights membranoproliferative glomerulonephritis (MPGN) linked to Schistosoma hematobium infection, leading to kidney failure.

Keywords:

Membranoproliferative glomerulonephritis Schistosomia hematobium nephrotic syndrome

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Published on: January 14, 2018

Area of Science:

Tropical medicine
Nephrology
Parasitology

Background:

Schistosomiasis is a major tropical parasitic disease with significant urological impact.
Glomerular injury is an uncommon complication, primarily associated with Schistosoma mansoni.

Observation:

A young Senegalese boy presented with steroid-resistant nephrotic syndrome.
Renal biopsy revealed type 1 membranoproliferative glomerulonephritis (MPGN).
Schistosoma hematobium eggs surrounded by granuloma were identified in the biopsy.

Findings:

This case demonstrates a rare association between Schistosoma hematobium infection and MPGN.
The patient experienced progression to end-stage renal disease within one year despite treatment.

Implications:

Early detection and prevention of schistosomiasis are crucial in at-risk populations.
This case underscores the need to consider schistosomiasis in the differential diagnosis of nephrotic syndrome in endemic areas.