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Related Concept Videos

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The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
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Tooth Anatomy01:21

Tooth Anatomy

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Related Experiment Video

Updated: May 29, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
07:15

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

[Relationship between periodontitis and systemic diseases].

S Jepsen1, M Kebschull, J Deschner

  • 1Poliklinik für Parodontologie, Zahnerhaltung und Präventive Zahnheilkunde, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Deutschland. jepsen@uni-bonn.de

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
|September 3, 2011
PubMed
Summary
This summary is machine-generated.

Periodontitis, a common gum disease, is linked to diabetes and atherosclerosis. Treating gum infections may improve diabetes management and reduce cardiovascular risks.

Related Experiment Videos

Last Updated: May 29, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
07:15

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

Area of Science:

  • Oral health
  • Systemic diseases
  • Inflammatory conditions

Background:

  • Periodontitis is a prevalent, biofilm-induced inflammatory disease affecting the periodontium.
  • Emerging evidence links periodontal infections to systemic conditions like diabetes and atherosclerosis.
  • A significant bidirectional relationship exists between periodontitis and diabetes.

Purpose of the Study:

  • To explore the systemic implications of periodontal infections.
  • To elucidate the intricate relationship between periodontitis and diabetes.
  • To investigate the association between periodontitis and atherosclerosis.

Main Methods:

  • Review of current scientific literature on periodontitis and its systemic links.
  • Analysis of the bidirectional relationship between periodontitis and diabetes.
  • Examination of periodontitis as a risk factor for atherosclerosis and related diseases.

Main Results:

  • Diabetes exacerbates periodontitis, complicating glycemic control and increasing complication risks.
  • Periodontal infections are recognized as independent risk factors for atherosclerosis and cardiovascular diseases.
  • Periodontal therapy demonstrates potential positive impacts on subclinical atherosclerosis markers.

Conclusions:

  • Integrated management of periodontitis and diabetes is crucial for optimal health outcomes.
  • Effective glycemic control is essential for successful periodontal treatment.
  • Addressing periodontal infections may mitigate systemic health risks, including cardiovascular events.