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Related Concept Videos

Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
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Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
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Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.

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Related Experiment Video

Updated: May 29, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

[Postpartum depression screening scales: a systematic review].

Juliana Machado Schardosim1, Elizeth Heldt

  • 1UFRGS, Rio Grande do Sul, Brasil.

Revista Gaucha De Enfermagem
|September 6, 2011
PubMed
Summary

This review found that postpartum depression (PPD) screening scales, particularly the Edinburgh Postpartum Depression Scale (EPDS), are widely used in research to identify PPD in women up to 16 weeks after childbirth.

Area of Science:

  • Obstetrics and Gynecology
  • Psychiatry
  • Public Health

Background:

  • Postpartum depression (PPD) is a significant maternal mental health concern.
  • Effective screening tools are crucial for early identification and intervention.

Purpose of the Study:

  • To systematically review postpartum depression (PPD) screening scales used in women up to 16 weeks postpartum.
  • To assess the definition and validation of these screening instruments.

Main Methods:

  • A systematic review of articles from four databases was conducted.
  • Inclusion criteria required precise definition and validation of screening instruments.
  • 18 articles were included from an initial search of 424 abstracts.

Main Results:

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Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
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Last Updated: May 29, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
07:30

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Published on: June 10, 2013

  • Screening periods ranged from 2-10 days postpartum, with retesting between 8-16 weeks.
  • PPD prevalence in the sampled studies varied from 8.8% to 40%.
  • The Edinburgh Postpartum Depression Scale (EPDS) was the most frequently utilized scale.

Conclusions:

  • Screening scales are commonly employed in research for PPD identification.
  • These tools can aid in the care of pregnant and postpartum patients.
  • Further research on validated screening tools is essential for maternal mental health care.