Give or take? Intravenous immunoglobulin or plasma exchange for Guillain-Barré syndrome

Richard A C Hughes1

  • 1Cochrane Neuromuscular Disease Group, MRC Centre for Neuromuscular Disease, PO Box 114, National Hospital for Neurology and Neurosurgery, 8-11 Queen Square, London WC1N 3BG, UK. rhughes11@btinternet.com

A new randomised controlled trial suggested that plasma exchange hastened removal from the ventilator in mechanically ventilated children with Guillain-Barré syndrome compared with intravenous immunoglobulin. Two larger trials in adults showed the opposite result.

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