Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Esophageal Achalasia01:27

Esophageal Achalasia

Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...
Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which leads...
Myasthenia Gravis ll: Pathophysiology01:22

Myasthenia Gravis ll: Pathophysiology

The disease process of myasthenia gravis begins at the neuromuscular junction, where antibodies attack key proteins needed for muscle activation. This immune reaction weakens signal transmission, leading to the characteristic muscle fatigue and weakness that define the condition.Immune-Mediated DamageIn most individuals, antibodies target acetylcholine receptors (AChRs) on the postsynaptic membrane of muscle cells. By blocking acetylcholine binding, these antibodies prevent the nerve signal...
Hiatal Hernia01:25

Hiatal Hernia

A hiatal hernia is the abnormal protrusion of the stomach or other abdominal organs through the esophageal hiatus of the diaphragm into the thoracic cavity.Normally, the gastroesophageal junction (GEJ) lies below the diaphragm and is supported by the phrenoesophageal membrane, the diaphragmatic crura, and connective tissues. Weakening of these structures—due to aging, congenital defects like a short esophagus, or increased intra-abdominal pressure from coughing, obesity, pregnancy, or heavy...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mentor, Coach, Sponsor: Who, Why, How.

Journal of the American College of Surgeons·2024
Same author

Surrogate Perception of Disability after Hospitalization for Traumatic Brain Injury.

Journal of the American College of Surgeons·2024
Same author

Shared Decision-Making in General Surgery: Prospective Comparison of Telemedicine vs In-Person Visits.

Journal of the American College of Surgeons·2023
Same author

Characterization of Acidosis in Trauma Patient.

Journal of emergencies, trauma, and shock·2020
Same author

Hemorrhage-Control Training in Medical Education.

Journal of medical education and curricular development·2020
Same author

Educational and Training Lessons from the COVID-19 Pandemic: We Must Prepare for the Next Pandemic.

Journal of the American College of Surgeons·2020
Same journal

Social Determinants of Health, Health Disparities, and Surgical Equity.

The Surgical clinics of North America·2026
Same journal

Beyond the Scalpel's Reach.

The Surgical clinics of North America·2026
Same journal

Stepwise Solutions-Society.

The Surgical clinics of North America·2026
Same journal

Stepwise Solutions-Hospitals.

The Surgical clinics of North America·2026
Same journal

Stepwise Solutions for Providers.

The Surgical clinics of North America·2026
Same journal

Stepwise Solutions-Patients Social Determinants of Health, Health Disparities, and Surgical Equity.

The Surgical clinics of North America·2026
See all related articles

Related Experiment Video

Updated: May 29, 2026

Robotic Myotomy and Partial Fundoplication for Achalasia
11:19

Robotic Myotomy and Partial Fundoplication for Achalasia

Published on: August 11, 2023

Achalasia.

William C Beck1, Kenneth W Sharp

  • 1Division of General Surgery, Department of Surgery, Vanderbilt University Medical Center, Vanderbilt University, 1161 Medical Center Drive, Room D-5203 MCN, Nashville, TN 37232-2577, USA.

The Surgical Clinics of North America
|September 6, 2011
PubMed
Summary
This summary is machine-generated.

This review covers achalasia, a rare esophageal disorder. Laparoscopic Heller myotomy with fundoplication offers a safe and effective treatment for achalasia.

More Related Videos

Robotic Heller Myotomy for Advancements in Surgical Management of Achalasia
09:46

Robotic Heller Myotomy for Advancements in Surgical Management of Achalasia

Published on: February 16, 2024

Use of the Scissor-Type Knife During the Peroral Endoscopy Myotomy Procedure for the Treatment of Achalasia
06:42

Use of the Scissor-Type Knife During the Peroral Endoscopy Myotomy Procedure for the Treatment of Achalasia

Published on: March 3, 2023

Related Experiment Videos

Last Updated: May 29, 2026

Robotic Myotomy and Partial Fundoplication for Achalasia
11:19

Robotic Myotomy and Partial Fundoplication for Achalasia

Published on: August 11, 2023

Robotic Heller Myotomy for Advancements in Surgical Management of Achalasia
09:46

Robotic Heller Myotomy for Advancements in Surgical Management of Achalasia

Published on: February 16, 2024

Use of the Scissor-Type Knife During the Peroral Endoscopy Myotomy Procedure for the Treatment of Achalasia
06:42

Use of the Scissor-Type Knife During the Peroral Endoscopy Myotomy Procedure for the Treatment of Achalasia

Published on: March 3, 2023

Area of Science:

  • Gastroenterology
  • Esophageal Motility Disorders

Background:

  • Achalasia is a rare esophageal motility disorder.
  • It is characterized by absent esophageal peristalsis and lower esophageal sphincter (LES) dysfunction.
  • Diagnosis and treatment options for achalasia are reviewed.

Purpose of the Study:

  • To review the diagnosis and treatment of achalasia.
  • To discuss various therapeutic interventions for this condition.

Main Methods:

  • Review of existing literature on achalasia diagnosis and treatment.
  • Discussion of pharmacological, endoscopic, and surgical management options.

Main Results:

  • Several treatment options exist for achalasia, including medications (nitrates, calcium channel blockers), botulinum toxin injection, and pneumatic dilation.
  • Laparoscopic Heller myotomy combined with partial fundoplication is presented as a minimally invasive, safe, and effective long-term treatment.
  • This surgical approach offers low morbidity and mortality rates.

Conclusions:

  • Achalasia requires careful diagnosis and tailored treatment.
  • Laparoscopic Heller myotomy with partial fundoplication is a durable and effective option for managing achalasia.
  • Minimally invasive surgical techniques provide favorable outcomes for patients.