Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Onchocerciasis.

H R Taylor1

  • 1Dana Center for Preventive Ophthalmology, Wilmer Institute, Johns Hopkins University, Baltimore, Maryland 21205.

International Ophthalmology
|May 1, 1990
PubMed
Summary
This summary is machine-generated.

Ivermectin, an annual oral dose, effectively suppresses onchocerciasis, a parasitic disease causing blindness in millions. Community-based distribution programs offer hope for controlling this major blinding scourge.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence and associations of presenting near-vision impairment in the Australian National Eye Health Survey.

Eye (London, England)·2018
Same author

Prevalence and causes of vision loss in Southeast Asia and Oceania: 1990-2010.

The British journal of ophthalmology·2014
Same author

The roadmap to close the gap for vision--diabetes-related eye care in the Indigenous Australian population.

Diabetic medicine : a journal of the British Diabetic Association·2013
Same author

Prevalence of diabetic retinopathy in Type 2 diabetes in developing and developed countries.

Diabetic medicine : a journal of the British Diabetic Association·2013
Same author

An emergent science on the brink of irrelevance: a review of the past 8 years of DNA barcoding.

Molecular ecology resources·2012
Same author

Microbiological and clinical profiles of patients with microbial keratitis residing in nursing homes.

The British journal of ophthalmology·2009

Area of Science:

  • Medical Parasitology
  • Ophthalmology
  • Tropical Diseases

Background:

  • Onchocerciasis, caused by Onchocerca volvulus, affects 80 million globally, leading to blindness in 1-2 million.
  • In endemic regions, over 50% of the population risks blindness from this parasitic infection.
  • Direct invasion of the eye by microfilariae is a primary cause of onchocerciasis-related visual impairment.

Purpose of the Study:

  • To highlight the impact of onchocerciasis as a blinding disease.
  • To introduce ivermectin as a revolutionary treatment.
  • To discuss the potential of mass ivermectin distribution for disease control.

Main Methods:

  • The abstract discusses the efficacy of an annual oral dose of ivermectin.
  • It mentions the suppression of disease manifestations with a 150 mg/kg dosage.

Related Experiment Videos

  • Community-based mass distribution programs are noted as a key strategy.

    • Main Results:

    • Ivermectin treatment completely suppresses onchocerciasis manifestations.
    • Annual oral doses of 150 mg/kg are effective.
    • Mass distribution programs are underway for disease control.

    Conclusions:

    • Ivermectin has revolutionized onchocerciasis treatment.
    • Community-based ivermectin distribution promises control of this blinding disease.
    • The drug offers a significant advancement in managing a major global health issue.