Related Experiment Videos
Effects of chronic beta-carotene supplementation on vitamin K status in adults
L M Canfield1, J J Corrigan, P M Plezia
1Department of Biochemistry, University of Arizona, Tucson 85724.
Nutrition and Cancer
|January 1, 1990
Abstract:
Plasma vitamin K concentrations and prothrombin coagulation activity were determined in 26 normal adults who had received daily beta-carotene supplementation (0, 15, 30, or 60 mg) for six months. Neither plasma vitamin K nor coagulation activity were significantly decreased at any supplementation level. Thus, chronic beta-carotene supplementation, even at high daily doses, is not expected to result in clinical vitamin K deficiency. The data suggest separate mechanisms for intestinal absorption of beta-carotene and vitamin K.