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Updated: May 29, 2026

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
Diffusion-weighted magnetic resonance imaging of the musculoskeletal system: an emerging technology with potential to
1University of South Carolina, School of Public Health, Blatt PE Center, 1300 Wheat Street, Columbia, SC 29208, USA. pbeattie@mailbox.sc.edu
Abstract:
Diffusion-weighted imaging (DWI) is an application of magnetic resonance imaging that allows the measurement of water movement within and between tissues. Originally developed as a way of detecting early signs of stroke or brain disease, DWI is now being used to study physiologic events within the musculoskeletal system. The accurate measurement of water diffusion can provide important information regarding tissue responses associated with trauma and disease, as well as offer insight toward the mechanism by which physical therapy interventions affect tissues. The purpose of this paper is to discuss the rationale for DWI and its potential clinical and research applications for patients with musculoskeletal disorders. Specific examples of the use of DWI for patients with painful spinal disorders are used as illustrations.
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