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Related Concept Videos

Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Fibril-associated Collagen01:11

Fibril-associated Collagen

Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
Compact Bone01:27

Compact Bone

Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
Porosity in Cement Paste01:18

Porosity in Cement Paste

The porosity of concrete is a measure of the void spaces within its structure. These spaces impact its strength and durability significantly. When water and cement interact, a chemical reaction called hydration creates a semi-solid paste. This paste includes combined water, making up approximately 23% of the cement's dry mass, and gel water, which fills minuscule voids known as gel pores, accounting for about 28% of the cement gel volume.
The balance of water to cement in the mix is critical—it...
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Spongy Bone01:09

Spongy Bone

All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...

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Radiographic analysis of ameloblastoma: a retrospective study.

Indian journal of dental research : official publication of Indian Society for Dental Research·2013
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Updated: May 29, 2026

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
08:07

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

Published on: April 12, 2019

Cemento-ossifying fibroma.

Chandramani More1, Krushna Thakkar, Mukesh Asrani

  • 1Department of Oral Medicine, Diagnosis and Radiology, K. M. Shah Dental College and Hospital, Sumandeep Vidyapeeth University, Piparia, Vadodara, Gujarat, India. drchandramanimore@rediffmail.com

Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research
|September 6, 2011
PubMed
Summary
This summary is machine-generated.

Cemento-ossifying fibromas (COFs) are benign jaw tumors typically affecting adult females. Surgical resection is the primary treatment, with rare recurrences and no response to radiotherapy.

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Last Updated: May 29, 2026

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
08:07

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

Published on: April 12, 2019

Area of Science:

  • Oral and Maxillofacial Surgery
  • Pathology
  • Oncology

Background:

  • Cemento-ossifying fibromas (COFs) are benign fibro-osseous lesions of the jaws.
  • They predominantly affect adult females in their third and fourth decades.
  • Commonly found in the mandibular premolar/molar region.

Observation:

  • COFs exhibit slow, expansile growth, typically centrally located within the jaw.
  • Radiographically, they present as well-defined, encapsulated, unilocular or multilocular masses with mixed radiodensities.
  • While generally benign, some lesions can present as aggressive gigantiform masses.

Findings:

  • Surgical resection is the definitive treatment for COFs.
  • These tumors are radioinsensitive, meaning radiotherapy is ineffective.
  • Recurrences after surgical removal are uncommon.

Implications:

  • Accurate diagnosis is crucial due to overlapping features with other fibro-osseous lesions.
  • Understanding COF characteristics guides appropriate surgical management.
  • Distinguishing COFs from other lesions prevents misclassification and ensures optimal patient outcomes.