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Published on: May 10, 2024
Antibiotic prescribing pattern in paediatric in patients with first time wheezing
Soumya Patra1, Varinder Singh, Harish K Pemde
1Department of Paediatrics, Lady Hardinge Medical College & associated Kalawati Saran Children's Hospital, New Delhi, India. dr_soumyapatra@rediffmail.com
Antibiotic use in first-time wheezing infants is common. Crackles and abnormal chest X-rays often lead to antibiotic prescriptions, despite similar outcomes.
Area of Science:
- Pediatrics
- Infectious Diseases
- Respiratory Medicine
Background:
- First-time acute wheezing in infants represents a critical group for reducing unnecessary antibiotic prescriptions.
- Antibiotic overuse in pediatric respiratory infections is a significant public health concern.
Purpose of the Study:
- To assess the influence of clinical, laboratory, and radiological findings on antibiotic prescribing decisions in infants with first-time wheezing.
- To identify specific criteria that may justify antibiotic use in this population.
Main Methods:
- A prospective study involving 47 healthy infants with first-time wheezing was conducted.
- Infants received standard care including oxygen and bronchodilators, with or without antibiotics.
- Statistical analysis compared antibiotic-treated (n=23) and non-antibiotic-treated (n=24) groups to identify predictors of antibiotic use.
Main Results:
- The mean age of participants was 5.8 months.
- Crackles on auscultation and radiographic abnormalities were key factors influencing antibiotic prescription.
- No significant differences in clinical outcomes were observed between the groups.
Conclusions:
- Antibiotic prescribing remains prevalent for infants experiencing their first episode of wheezing.
- Clinical signs like crackles and radiological findings frequently trigger antibiotic use in these cases, irrespective of outcome.
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