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Updated: May 29, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
[Congenital linear nevus sebaceus].
Anders Linnemann1, Anette Bygum, Jesper Fenger-Grøn
1Pædiatrisk Afdeling, Sygehus Lillebælt, 6000 Kolding, Denmark. anders.linnemann@slb.regionsyddanmark.dk
A rare congenital skin condition, nevus sebaceous, presented unusually along Blaschko lines on an extremity. This case highlights the importance of recognizing atypical presentations to avoid misdiagnosis and unnecessary treatments.
Area of Science:
- Dermatology
- Pathology
- Genetics
Background:
- Nevus sebaceous is a congenital hamartoma typically affecting the head and neck.
- Blaschko lines represent patterns of somatic mosaicism, often seen in various dermatoses.
Observation:
- An unusual case of nevus sebaceous presented as a linear, papulovesicular lesion along the Blaschko lines on the lower extremity.
- The clinical presentation mimicked other conditions such as incontinentia pigmenti or infection.
Findings:
- Biopsy confirmed the diagnosis of nevus sebaceous, despite its atypical location and morphology.
- The lesion's linear arrangement followed Blaschko lines, suggesting a mosaic pattern of development.
Implications:
- Recognizing atypical presentations of nevus sebaceous is crucial for accurate diagnosis.
- This case underscores the need for careful differential diagnosis to prevent unnecessary investigations and treatments for patients.
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