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Related Experiment Video

Updated: May 29, 2026

Doppler Ultrasonography for Live Imaging and Quantification of Ovarian Vascular Function in Mice
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Is ovarian volume estimation reliable when compared with true volume?

Gurkan Bozdag1, Mehmet Coskun Salman, Sezcan Mumusoglu

  • 1Department of Obstetrics and Gynecology, Hacettepe University School of Medicine, Ankara, Turkey. gbozdag@hacettepe.edu.tr

American Journal of Obstetrics and Gynecology
|September 7, 2011
PubMed
Summary

Three-dimensional (3D) ultrasonography (USG) shows improved accuracy in estimating true ovarian volume (OV) compared to 2D USG. This suggests 3D USG may offer a more precise method for ovarian volume assessment.

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Area of Science:

  • Reproductive Medicine
  • Medical Imaging
  • Gynecology

Background:

  • Accurate ovarian volume (OV) assessment is crucial in gynecological diagnostics.
  • Traditional 2-dimensional (2D) ultrasonography (USG) has limitations in precise OV measurement.
  • 3-dimensional (3D) USG offers potential for enhanced volumetric accuracy.

Purpose of the Study:

  • To compare the accuracy of 2D and 3D USG in estimating true ovarian volume (OV).
  • To evaluate the agreement between ultrasonographic estimations and post-oophorectomy true OV.
  • To determine which USG modality provides a more precise measurement of ovarian volume.

Main Methods:

  • Prospective enrollment of 46 ovaries from 30 patients undergoing oophorectomy.
  • Preoperative assessment of ovarian volume using both 2D and 3D ultrasonography (USG).
  • Comparison of USG-derived volumes with true ovarian volume calculated using Archimedes' principle post-oophorectomy.

Main Results:

  • Correlation coefficients for 2D and 3D USG with true OV were comparable (0.65 vs 0.67).
  • Mean bias between 3D USG and true OV (0.33 mL) was lower than for 2D USG (1.41 mL).
  • 3D USG underestimated OV by 11%, while 2D USG overestimated it by 18% compared to true OV.

Conclusions:

  • 3-dimensional ultrasonography (USG) demonstrates a lower mean bias in estimating ovarian volume (OV) compared to 2D USG.
  • 3D USG may offer improved precision for ovarian volume assessment in clinical practice.
  • Further validation of 3D USG for OV measurement is warranted.