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Updated: May 29, 2026

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
Published on: August 2, 2017
Quantitative modelling of sleep dynamics
P A Robinson1, A J K Phillips, B D Fulcher
1School of Physics, University of Sydney, Sydney, NSW 2006, Australia. p.robinson@physics.usyd.edu.au
Abstract:
Arousal is largely controlled by the ascending arousal system of the hypothalamus and brainstem, which projects to the corticothalamic system responsible for electroencephalographic (EEG) signatures of sleep. Quantitative physiologically based modelling of brainstem dynamics theory is described here, using realistic parameters, and links to EEG are outlined. Verification against a wide range of experimental data is described, including arousal dynamics under normal conditions, sleep deprivation, stimuli, stimulants and jetlag, plus key features of wake and sleep EEGs.
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