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Updated: May 29, 2026

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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
Summary
This clinical overview covers sickle cell disease (SCD) management, including prevention, diagnosis, and treatment. It offers CME credits for ACP members and subscribers, with options for non-subscribers to access the content.
Area of Science:
- Hematology
- Clinical Medicine
Background:
- Sickle cell disease (SCD) is a genetic blood disorder requiring comprehensive clinical management.
- Effective prevention, diagnosis, and treatment strategies are crucial for improving patient outcomes.
Purpose of the Study:
- To provide a clinical overview of sickle cell disease.
- To focus on key aspects of SCD care including prevention, diagnosis, treatment, and practice improvement.
Main Methods:
- Content is derived from clinical information and education resources of the American College of Physicians (ACP).
- Resources include Physicians' Information and Education Resource (PIER) and Medical Knowledge and Self Assessment Program (MKSAP).
- Editorial development involves Annals of Internal Medicine editors, ACP's Medical Education and Publishing division, science writers, and physician writers.
Main Results:
- The issue offers a comprehensive clinical overview of sickle cell disease.
- It details prevention, diagnosis, treatment, and practice improvement strategies.
- Patient information resources are also provided.
Conclusions:
- This issue serves as a valuable resource for clinicians managing sickle cell disease.
- It emphasizes a multidisciplinary approach to SCD care.
- Access to detailed information is available through referenced ACP resources.
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