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Updated: May 29, 2026

Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury
Published on: June 21, 2019
Incidence of epilepsy: a systematic review and meta-analysis
Anthony K Ngugi1, S M Kariuki, C Bottomley
1Centre for Geographic Medicine Research-Coast, KEMRI, Kilifi 80108, Kenya. angugi@kilifi.kemri-wellcome.org
Objective:
To estimate the pooled incidence of epilepsy from published studies and investigate sources of heterogeneity in the estimates.
Methods:
We searched online databases for incidence studies and used meta-analytic methods to analyze the data.
Results:
Thirty-three articles met the entry criteria. The median incidence of epilepsy was 50.4/100,000/year (interquartile range [IQR] 33.6-75.6), while it was 45.0 (IQR 30.3-66.7) for high-income countries and 81.7 (IQR 28.0-239.5) for low- and middle-income countries. Population-based studies had higher incidence estimates than hospital-based studies (p = 0.02) while retrospective study design was associated with lower estimates than prospective studies (p = 0.04).
Conclusion:
We provide data that could potentially be used to assess the burden and analyze the trends in incidence of epilepsy. Our results support the need for large population-based incidence studies of epilepsy.
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