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Related Concept Videos

Factors Affecting Dissolution: Polymorphism, Amorphism and Pseudopolymorphism01:21

Factors Affecting Dissolution: Polymorphism, Amorphism and Pseudopolymorphism

Polymorphism refers to the existence of a drug substance in multiple crystalline forms, known as polymorphs. Recently, this term has been expanded to include solvates (forms containing a solvent), amorphous forms (non-crystalline forms), and desolvated solvates (forms from which the solvent has been removed).
Some polymorphic crystals possess lower aqueous solubility than their amorphous counterparts, leading to incomplete absorption. For instance, the oral suspension of Chloramphenicol, which...
SBAR I: Understanding the Concept01:29

SBAR I: Understanding the Concept

Effective communication among healthcare professionals during hand-off reporting is essential to delivering safe and continuous patient care. Common professional interactions include reports to healthcare team members, hand-off, and transfer reports. Nurses routinely report information to other healthcare team members and also urgently contact healthcare providers to report changes in patient status.
Standardized methods of communication have been developed to ensure that information is...
SBAR II: Application of SBAR01:14

SBAR II: Application of SBAR

SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
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Bioequivalence: Overview01:16

Bioequivalence: Overview

Pharmaceutical equivalents, by definition, are drug products with the same active ingredient in the same quantities, encapsulated in identical dosage forms, and intended for the same administration routes. These pharmaceutical equivalents are deemed bioequivalent if the bioavailability of the active entity in the drug preparations is similar. Moreover, pharmaceutical equivalents demonstrating bioequivalence are also regarded as therapeutically equivalent. This means that when used as directed,...
Impact of Schemas01:30

Impact of Schemas

Schemas are cognitive structures that provide a framework for interpreting and organizing social information. They help individuals navigate complex environments by offering expectations about people, events, and behaviors. Schemas influence attention, encoding, and retrieval processes, thereby shaping the entire trajectory of information processing in social contexts.Attention and Cognitive LoadDuring initial attention, schemas function as filters that prioritize schema-consistent information,...
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Drug Products: Biologics, Biosimilars and Interchangeables

Biologics, derived from living sources such as humans, animals, or microorganisms, represent a significant category of pharmaceuticals. These complex molecules, developed through advanced biotechnological methods or purified from natural sources, include essential medical treatments like insulin and growth hormones. The complexity of biologics arises from their large molecular structures and the intricate processes required for their production, making them distinct from conventional...

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Related Experiment Videos

ARGOS policy brief on semantic interoperability.

Dipak Kalra1, Mark Musen, Barry Smith

  • 1University College London, UK. d.kalra@ucl.ac.uk

Studies in Health Technology and Informatics
|September 7, 2011
PubMed
Summary
This summary is machine-generated.

Achieving semantic interoperability for electronic health records (EHRs) requires standardized clinical information and quality-assured semantic resources. Collaborative efforts between Europe and the US are crucial for advancing EHR data sharing and analysis.

Related Experiment Videos

Area of Science:

  • Health Informatics
  • Information Science
  • Computer Science

Background:

  • Semantic interoperability is a key challenge for sharing electronic health records (EHRs) across heterogeneous systems.
  • Previous workshops (2010-2011) involving European and US experts highlighted lessons learned and approaches for addressing this challenge.
  • Effective EHR data exploitation for patients, professionals, and research necessitates overcoming semantic barriers.

Purpose of the Study:

  • To summarize the challenges and importance of semantic interoperability in EHRs.
  • To outline existing areas of semantic innovation applicable to EHR data sharing.
  • To propose actionable next steps for transatlantic collaboration in advancing EHR interoperability.

Main Methods:

  • Policy brief summarizing findings from ARGOS Trans-Atlantic Observatory workshops.
  • Analysis of challenges in achieving semantic interoperability for EHRs.
  • Identification of semantic innovation areas and proposed solutions.

Main Results:

  • Semantic interoperability demands standardized clinical information and semantic resources (e.g., archetypes, templates, ontologies).
  • Requires global engagement with professional bodies for clinical information standards development.
  • Need for improved definition, validation, dissemination, and user education for semantic resources.

Conclusions:

  • Scaling up authorship, acceptance, and adoption of clinical information standards is urgent.
  • Harmonizing existing standardization efforts and assuring artifact quality are critical.
  • Establishing end-to-end governance for the development and adoption of semantic interoperability solutions is essential.