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Disorders of the Urinary System

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The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
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Diabetes Insipidus I: Introduction

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Definition Diabetes insipidus is a disorder marked by the production of large amounts of dilute urine because of impaired vasopressin production, release, or kidney response. The lack of effective vasopressin action limits water reabsorption in the renal collecting ducts, which leads to excessive urinary water loss and intense thirst.Clinical PresentationIndividuals with diabetes insipidus report persistent thirst and very high urine output. In severe cases, fluid intake can reach up to 20...

Diabetic Nephropathy

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Related Experiment Video

Updated: May 29, 2026

Real-Time Void Spot Assay

Real-Time Void Spot Assay

Published on: February 10, 2023

Bladder dysfunction in patients with diabetes.

Christopher S Gomez¹, Prashanth Kanagarajah, Angelo E Gousse

¹Bladder Health and Reconstructive Urology Institute, Memorial Hospital Miramar, 1951 Southwest 172nd Avenue, Suite #408, Miramar, FL 33029, USA.

Current Urology Reports

|September 7, 2011

Summary

Diabetes mellitus (DM) causes significant voiding dysfunction, including incomplete bladder emptying and incontinence. Further research is critical to address this common complication.

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Published on: April 27, 2014

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Last Updated: May 29, 2026

Real-Time Void Spot Assay

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Published on: February 10, 2023

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice

Published on: April 27, 2014

Area of Science:

Urology
Endocrinology
Diabetology

Background:

Diabetes mellitus (DM) is a global epidemic.
Voiding dysfunction is a common and burdensome complication of DM.
Research into diabetic voiding dysfunction lags behind other DM complications like retinopathy and nephropathy.

Purpose of the Study:

To review current concepts of diabetic voiding dysfunction.
To critically analyze the available evidence on DM-related lower urinary tract dysfunction.

Main Methods:

Literature review of recent studies on diabetic voiding dysfunction.
Critical analysis of existing evidence.

Main Results:

DM predisposes patients to a wide spectrum of lower urinary tract dysfunction.
Manifestations range from diabetic cystopathy (incomplete emptying) to urgency incontinence.

Conclusions:

Diabetic voiding dysfunction is a critical and under-researched complication of DM.
Understanding and addressing these issues is essential for patient care.