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[Diffuse gastric cancer associated with Ménétrier's disease]
Lisandro Pereyra1, Estanislao J Gómez, José M Mella
1Servicio de Gastroenterología, Hospital Alemán, Ciudad Autónoma de Buenos Aires, Argentina. lisandro_pereyra@hotmail.com
Acta Gastroenterologica Latinoamericana
|September 8, 2011
Summary
Ménétrier
Area of Science:
- Gastroenterology
- Oncology
Background:
- Ménétrier's disease is a rare hypertrophic gastropathy of unknown etiology.
- Its malignant potential remains controversial, with limited evidence of gastric cancer association.
Observation:
- A 72-year-old male presented with epigastric pain, early satiety, weight loss, and asthenia.
- Endoscopy revealed nodular gastric mucosa with enlarged folds; CT showed gastric wall thickening and adenopathies.
Findings:
- Histopathology confirmed Ménétrier's disease with diffuse infiltration of a highly undifferentiated adenocarcinoma (plastic linitis).
- The patient underwent subtotal gastrectomy for diffuse gastric adenocarcinoma.
Implications:
- This case highlights the rare association between Ménétrier's disease and diffuse gastric adenocarcinoma.
- Further research is needed to understand the potential malignant transformation in Ménétrier's disease.
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