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[Pesticide poisoning in Moroccan children: epidemiological and prognostic aspects (1990-2008)]
Sanae Achour1, Asmae Khattabi, Naïma Rhalem
1Service de Pharmaco-Toxiocolgie, Laboratoire central d'analyses médicales, CHU Hassan II de Fés, 18500 Fés-Maroc.
Insights
Acute pesticide poisoning in children is a significant issue in Morocco. Accidental poisonings, particularly from organophosphates, are common, with rural origin and voluntary circumstances increasing fatality risk.
Area of Science:
- Toxicology
- Epidemiology
- Pediatrics
Context:
- Acute pesticide poisoning (APP) in children presents a public health challenge.
- Data from the Moroccan Poison Control Center (CAPM) spans 18 years (1990-2008).
Purpose:
- To define the epidemiological profile of childhood APP in Morocco.
- To identify factors predicting mortality in pediatric pesticide poisoning cases.
Summary:
- A retrospective analysis of 2,672 APP cases in children treated by CAPM was conducted.
- Organophosphates were the most common agent (50.7%), with accidental ingestion in 87.1% of cases.
- The overall case fatality rate was 3.3%, with rural origin, voluntary circumstances, and specific chemical classes significantly associated with fatal outcomes.
Impact:
- Findings highlight the need for targeted preventive strategies to reduce childhood pesticide poisoning in Morocco.
- Understanding risk factors can inform public health interventions and clinical management.
Objective:
The purpose of this paper is to describe the epidemiological profile of
Method:
the study is based on a retrospective study of all cases of APP collected by the CAPM over a period of eighteen years (January 1990 to December 2008). Univariate analysis was performed to identify risk factors.
Results:
2,672 cases of childhood poisoning by pesticide were collected. The mean age was 5.6 ± 4.57 years. The sex ratio was 1.12. The cause of poisoning was accidental in 87.1% of cases, followed by attempted suicide (12.1%). Organophosphates were the most frequent poison (50.7%), followed by alpha-chloralose (26.5%). The case fatality rate was 3.3%. Mortality was attributed to organophosphates in 30 cases, followed by inorganic derivatives (7 cases) and carbamates (6 cases). A univariate analysis comparing survivors and groups who died showed that rural origin (p = 0.04), voluntary circumstances (p = 0.001), and the type of chemical class of pesticide (p < 0.001) significantly influence fatal poisoning.
Conclusion:
Acute pesticide poisoning among children is a reality in Morocco. Preventive measures may be needed.
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