Related Experiment Video
Updated: May 29, 2026

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
Published on: February 28, 2025
[Pregnancy and poly-drug use: changes in patient population and care, 1999-2008]
Laurence Simmat-Durand1, Elsa Miossec, Stéphanie Toutain
1Université Paris Descartes CERMES3 équipe CESMAES-45 rue des Saints-Péres-75006 Paris.
Changes in drug use in the general French population over the last decade have also been observed among pregnant women. There have also been significant changes in the treatment of substance users. Data relating to maternal drug use and the treatment of drug-using mothers were collected based on a retrospective cohort of 170 newborns with mothers using at least two different substances. The decrease in the proportion of heroin-users, the rise of opiate maintenance treatments and cannabis, and the development of new forms of treatment are linked to shorter maternity stays for newborns and shorter treatments for neonatal abstinence syndrome. The percentage of preterm births and of children placed in foster care is also on the decrease. Changes in drug use among mothers and new forms of treatment given to mother-infant dyads may account for the decrease in treatment for NAS, the shorter length of hospital stays, and the decreasing number of children placed in foster care.
Changes in drug use in the general French population over the last decade have also been observed among pregnant women. There have also been significant changes in the treatment of substance users. Data relating to maternal drug use and the treatment of drug-using mothers were collected based on a retrospective cohort of 170 newborns with mothers using at least two different substances. The decrease in the proportion of heroin-users, the rise of opiate maintenance treatments and cannabis, and the development of new forms of treatment are linked to shorter maternity stays for newborns and shorter treatments for neonatal abstinence syndrome. The percentage of preterm births and of children placed in foster care is also on the decrease. Changes in drug use among mothers and new forms of treatment given to mother-infant dyads may account for the decrease in treatment for NAS, the shorter length of hospital stays, and the decreasing number of children placed in foster care.
Related Concept Videos
Drug Toxicity: Risk factors
Factors Affecting Drug Response: Overview
Drug Dosing: Geriatric Patients
Drug Therapy
Antianxiety Medications
Drug Abuse and Addiction: Pharmacological Phenomena
Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment
