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Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

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Best practice in primary care pathology: review 14.

J C Cabrera-Abreu¹, W S A Smellie, R Bowley

¹Department of Clinical Biochemistry, Royal Berkshire and Battle NHS Trust, Reading, UK.

Journal of Clinical Pathology

|September 8, 2011

Summary

This review provides best practice guidance for requesting specific tumour markers in primary care. It covers carbohydrate antigen 125, α-fetoprotein, and human chorionic gonadotropin, offering evidence-based recommendations.

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Comparative Lesions Analysis Through a Targeted Sequencing Approach

Comparative Lesions Analysis Through a Targeted Sequencing Approach

Published on: November 5, 2019

Area of Science:

Oncology
Clinical Biochemistry
Primary Care Medicine

Background:

Tumour marker (TM) requesting in primary care requires clear, evidence-based guidelines.
Previous reviews have addressed TM requesting; this paper focuses on specific markers.
Existing guidance needs periodic updates to incorporate new research and clinical insights.

Purpose of the Study:

To present best practice recommendations for requesting carbohydrate antigen 125 (CA-125), α-fetoprotein (AFP), and human chorionic gonadotropin (hCG) in primary care.
To consolidate current national and international guidance for these tumour markers.
To provide a referenced, question-and-answer format for easy clinical application.

Main Methods:

A standardized literature search was conducted for national/international guidance, consensus statements, health policy documents, and evidence-based reviews.
MEDLINE and EMBASE searches supplemented the literature review to identify primary research.
Information was synthesized to create question-answer based recommendations.

Main Results:

Recommendations for the appropriate use of CA-125, AFP, and hCG in primary care settings are provided.
The review consolidates evidence from multiple sources into actionable guidance.
The Q&A format facilitates quick access to relevant information for clinicians.

Conclusions:

This review offers updated, evidence-based best practices for requesting key tumour markers in primary care.
The recommendations aim to improve the appropriate utilization of CA-125, AFP, and hCG.
Future updates will ensure the guidance remains current with emerging scientific information.