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Updated: May 29, 2026

Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions
Published on: April 28, 2026
Dieulafoy lesion in the stomach
1Vakif Gureba Training and Research Hospital, Fatih, Istanbul, Turkey.
Dieulafoy disease, a rare cause of gastrointestinal bleeding from abnormal submucosal vessels, was successfully treated with surgical resection in a patient with a long-undiagnosed stomach lesion. The patient recovered without complications.
Area of Science:
- Gastroenterology
- Vascular Medicine
- Surgical Pathology
Background:
- Dieulafoy disease is an infrequent cause of significant gastrointestinal hemorrhage.
- Pathognomonic feature involves a large aberrant submucosal artery eroding into the gastrointestinal lumen.
- Etiology remains largely unknown, though associations with NSAID use and other comorbidities are noted.
Observation:
- A case report of a patient presenting with a long-standing, undiagnosed Dieulafoy lesion of the stomach.
- The patient underwent surgical resection for the condition.
- Postoperative recovery was uncomplicated.
Findings:
- Surgical resection is a viable and effective treatment option for Dieulafoy disease.
- Complete resolution of bleeding and symptoms was achieved postoperatively.
- Minimally invasive surgical techniques may offer favorable outcomes.
Implications:
- Highlights the importance of considering Dieulafoy disease in unexplained GI bleeding.
- Surgical management provides a definitive treatment for refractory or complex cases.
- Further research into the pathogenesis may lead to novel non-surgical therapeutic strategies.
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