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Cushing syndrome and the anesthesiologist, two case reports
1Department of Anesthesiology, Intensive Care, Emergency, and Toxicology, University Hospital Center "Mother Theresa", Tirana, Albania.
Insights
Managing Cushing's syndrome (CS) requires special anesthetic care. With careful monitoring and advanced techniques, patients undergoing adrenalectomy can achieve successful outcomes and improved recovery.
Area of Science:
- Endocrinology
- Anesthesiology
- Surgical Management
Background:
- Cushing's syndrome (CS) significantly impacts quality of life and increases mortality, primarily from cardiovascular complications.
- Key features include central obesity, moon facies, and metabolic disturbances like hyperglycemia and hypertension.
- These clinical manifestations complicate perioperative anesthetic management.
Observation:
- Two cases of Cushing's syndrome treated with adrenalectomy are presented.
- Specialized pre- and post-operative care protocols were implemented.
- Anesthesia induction preceded the adrenalectomy, with continuous intraoperative hemodynamic monitoring.
Findings:
- Advanced anesthetic techniques and meticulous monitoring were employed.
- Both patients experienced uneventful postoperative recovery.
- Effective management is achievable despite the challenges posed by CS.
Implications:
- Highlights the critical need for specialized anesthetic protocols in Cushing's syndrome patients.
- Demonstrates that successful surgical outcomes are possible with vigilant perioperative care.
- Emphasizes the importance of continuous monitoring for hemodynamic stability during and after adrenalectomy.
Abstract:
Cushing's syndrome (CS) is associated with reduced life quality and increased mortality, mostly due to cardiovascular disease. The features of this syndrome are central obesity, moon facies, facial plethora, supraclavicular fat pads, buffalo hump, and purple striae. Other complications include hyperglycemia, hypertension, proximal muscle weakness, skin thinning, menstrual irregularities, amenorrhea and osteopenia. These make perioperative and anesthetic management difficult and present a challenge to the operating team, especially the anaesthesiologist. In this paper, we present two such cases of CS, which were treated with adrenalectomy. We aim to highlight the special care and precautions that need to be taken while administering anesthesia, and in the post operatory period. Anaesthesia induction in the two cases of CS was done prior to the adrenalectomy procedure and special pre and post operative care was taken. Continuous intra operative monitoring of vitals and checking for the stability of the haemodynamics was performed. With adequate care and using advanced anesthetic techniques, the patients showed uneventful post operative recovery. Though the anesthetic management of patients with CS is difficult, desired results can be achieved with continuous monitoring and special precautions.
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