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Inducing Apical Periodontitis in Mice
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Severe external apical root resorption--local cause or genetic predisposition?

Kathrin Sehr1, Niko Christian Bock, Christos Serbesis

  • 1Department of Orthodontics, Medical Center for Dental and Oral Medicine, Justus Liebig University, Schlangenzahl 14, 35392, Giessen, Germany.

Journal of Orofacial Orthopedics = Fortschritte Der Kieferorthopadie : Organ/Official Journal Deutsche Gesellschaft Fur Kieferorthopadie
|September 8, 2011
PubMed
Summary

Severe external apical root resorption (SEARR) in maxillary incisors during multibracket (MB) treatment is rare, affecting only 0.5% of patients. Local factors, not genetics, likely predispose individuals to this condition.

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Area of Science:

  • Orthodontics
  • Dental Research
  • Periodontology

Background:

  • Genetic predisposition is thought to influence orthodontic root resorption.
  • Previous studies imply a uniform root resorption response across all teeth.

Purpose of the Study:

  • To determine the incidence and extent of severe external apical root resorptions (SEARR) in maxillary incisors.
  • To investigate SEARR during multibracket (MB) appliance treatment.

Main Methods:

  • Analysis of 3198 patients who completed MB treatment between 1991 and 2010.
  • Selection of subjects with SEARR (grade-IV, >1/3 root length) on at least one maxillary incisor.
  • Evaluation using pre- and post-treatment orthopantomograms, measuring crown and root length.

Main Results:

  • SEARR incidence in maxillary incisors was 0.5% (16 patients).
  • Median SEARR was 38.6% of initial root length (range: 33.4%-61.0%).
  • Only 12.5% of affected patients had SEARR in all four maxillary incisors.

Conclusions:

  • The incidence of SEARR in maxillary incisors during MB treatment is low (0.5%).
  • Local factors appear to be more significant than systemic/genetic factors in predisposing patients to SEARR.
  • The findings challenge the notion of a uniform genetic predisposition for root resorption.