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B lymphocytes as effector cells in the immunotherapy of cancer

Jukes P Namm1, Qiao Li, Xiangming Lao

  • 1University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, USA.

Journal of Surgical Oncology
|September 8, 2011
PubMed

Over the years, the role of B cells in the host immune response to malignancy has been overshadowed by our focus on T cells. Nevertheless, B cells play important roles as antigen-presenting cells and in the production of antibodies. Furthermore, B cells can function as effector cells that mediate tumor destruction on their own. This review will highlight the various functions of B cells that are involved in the host response to tumor.

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