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Updated: May 29, 2026

Infinium Assay for Large-scale SNP Genotyping Applications
Published on: November 19, 2013
[Polymorphic analysis of 5 Y-SNP loci in Han population of Jinan]
Shu-Yi Han1, Hong-Mei Gao, Mao-Xiu Zhang
1Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, China. hanshuyi2007@126.com
Objective:
To investigate polymorphism distribution of the 5 Y-SNP loci in Jinan Han population, and evaluate their potential in forensic application.
Methods:
Genotyping of 5 Y-SNP loci (M89, M9, M122, M134, M95) were executed in the sample of 103 unrelated Chinese male individuals in Jinan Han population by using fragment length discrepant allele specific PCR (FLDAS-PCR).
Results:
In 5 Y-SNP loci, genetic polymorphism were identified in Jinan Han population, and the ranges of gene diversity(GD) were 0.093 3-0.491 2. Twenty different haplotypes were observed and the haplotypes diversity (HD) was 0.867 9. Six different haplogroups were detected according to international association of Y chromosome nomenclature.
Conclusion:
Five Y-SNP loci and their haplogroups in Jinan Han population are highly polymorphic, which can provide more information for the genetic structure analysis and forensic genetics research in the region.
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