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Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors
Published on: September 10, 2013
Pyrophosphate-selective fluorescent chemosensor based on 1,8-naphthalimide-DPA-Zn(II) complex and its application for
Jun Feng Zhang1, Sooyeon Kim, Ji Hae Han
1Department of Chemistry and Research Institute for Natural Sciences, Korea University, Seoul 136-701, Korea.
Organic Letters
|September 9, 2011
Abstract:
A new zinc(II) complex with a two-dipicolylamine-substituted 1,8-naphthalimide for recognition of pyrophosphate with ratiometrical fluorescence changes in aqueous solution has been synthesized and characterized. Its biological application to monitor the intracellular pyrophosphate (PPi) was successfully demonstrated by the observation that the fluorescence of 1 was enhanced by the presence of the Zn(2+) ion and was quenched by addition of PPi.

