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Some effects of mechanical trauma on the development of primary cancers and their metastases

L Weiss1

  • 1Department of Experimental Pathology, Roswell Park Memorial Institute, Buffalo, NY.

Journal of Forensic Sciences
|May 1, 1990
PubMed

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...