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Updated: May 29, 2026
09:31
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Renal cell carcinoma with extensive oncocytic features.
Mana Moghadamfalahi1, Houda Alatassi
1Department of Pathology & Laboratory Medicine, University of Louisville, Louisville, KY 40202, USA.
International Journal of Surgical Pathology
|September 10, 2011
Summary
Oncocytic features in kidney tumors can mimic renal oncocytoma. This case highlights an unusual unclassified renal cell carcinoma with extensive oncocytic changes, emphasizing diagnostic challenges.
Area of Science:
- Nephrology
- Oncology
- Pathology
Background:
- Oncocytic features are characteristic of renal oncocytoma but can appear in other renal tumors.
- Unclassified renal cell carcinoma with oncocytic features constitutes a significant portion of challenging renal neoplasms.
- Recent descriptions of variants like mucinous tubular and spindle cell carcinoma with oncocytic changes add complexity.
Observation:
- This report details an unusual case of unclassified renal cell carcinoma exhibiting extensive oncocytic changes.
- The tumor presented morphological characteristics that could be mistaken for other renal neoplasms.
Findings:
- The extensive oncocytic changes in this unclassified renal cell carcinoma posed a diagnostic challenge.
- Distinguishing this entity from other oncocytic renal tumors is crucial for accurate diagnosis and treatment.
Implications:
- Accurate identification of renal tumors with oncocytic features is critical for appropriate patient management.
- Understanding these challenging variants improves diagnostic accuracy in renal pathology.
- Further research into the molecular and morphological spectrum of renal cell carcinoma is warranted.
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