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Published on: February 9, 2011
Panton-Valentine leukocidin-producing Staphylococcal aureus: report of four siblings
Kara Heelan1, Annette Murphy, Lesley-Ann Murphy
1Department of Dermatology, Galway University Hospital, Galway, Ireland. karaheelan@yahoo.com
Abstract:
Panton-Valentine leukocidin (PVL)-producing Staphylococcus aureus results in leukocyte destruction and tissue necrosis (Pediatric Dermatology 2007;24:401). It can be associated with a spectrum of clinical manifestations that range from localized staphylococcal skin infections to sometimes severe necrotizing pneumonia (Clin Infect Dis 1999;29:1128). We report a case of four siblings, three brothers whose atopic dermatitis was complicated by cutaneous lesions and furunculosis, while their 21-month-old sister had a fatal PVL positive staphylococcal pneumonia.
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