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Related Experiment Video

Updated: May 29, 2026

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
05:46

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

Metastatic choroidal paraganglioma.

Ann Schalenbourg1, Alexandre Moulin, Louis Guillou

  • 1Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland. ann.schalenbourg@fa2.ch

Ophthalmology
|September 13, 2011
PubMed
Summary

Malignant paraganglioma can spread to the choroid, presenting as a nonpigmented mass. Stereotactic radiotherapy effectively treated this rare ocular metastasis in a patient with widespread disease.

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Area of Science:

  • Ophthalmology
  • Oncology
  • Radiology

Background:

  • Malignant paraganglioma is a rare tumor with potential for metastasis.
  • Choroidal metastases are uncommon, and paraganglioma is an even rarer cause.
  • This case highlights the importance of considering rare diagnoses in ophthalmology.

Observation:

  • A 50-year-old male presented with a nonpigmented choroidal mass and retinal detachment.
  • Biopsy confirmed paraganglioma, with metastatic disease found in the vertebrae, mediastinum, and lungs.
  • The primary tumor origin remained unidentified.

Findings:

  • Stereotactic radiotherapy led to regression of the ocular tumor.
  • Recurrent disease in the contralateral eye also responded to radiotherapy.

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Last Updated: May 29, 2026

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
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Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma
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Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma

Published on: January 25, 2015

  • This represents the first reported case of choroidal paraganglioma.

    • Implications:

    • Malignant paraganglioma should be included in the differential diagnosis for nonpigmented choroidal masses.
    • Stereotactic radiation therapy demonstrates efficacy in managing choroidal paraganglioma.
    • This case expands the understanding of rare metastatic patterns in paraganglioma.