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Related Concept Videos

Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Extracellular Matrix01:26

Extracellular Matrix

Unlike epithelial tissue, which is composed of cells closely packed with little or no extracellular space in between, connective tissue cells are dispersed in a matrix. This extracellular matrix (ECM) is composed of fibrous proteins like collagen, elastin, and fibronectin in a ground substance consisting of interstitial fluid, cell adhesion proteins, and proteoglycans. The proteoglycans form a gel-like material in the spaces between cells and provide hydration, buffering, binding, and force...
The Extracellular Matrix01:42

The Extracellular Matrix

Overview
The Extracellular Matrix01:29

The Extracellular Matrix

Overview
In order to maintain tissue organization, many animal cells are surrounded by structural molecules that make up the extracellular matrix (ECM). Together, the molecules in the ECM maintain the structural integrity of tissue as well as the remarkable specific properties of certain tissues.
Composition of the Extracellular Matrix
The extracellular matrix (ECM) is commonly composed of ground substance, a gel-like fluid, fibrous components, and many structurally and functionally diverse...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

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Improving 2D and 3D Skin In Vitro Models Using Macromolecular Crowding
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Published on: August 22, 2016

Acellular dermal matrix in eyelid surgery.

John Symbas1, Clinton McCord, Foad Nahai

  • 1Private practice, Atlanta, Georgia, USA. johnsymbas@gmail.com

Aesthetic Surgery Journal
|September 13, 2011
PubMed
Summary
This summary is machine-generated.

This study updates previous findings on EnduraGen for eyelid surgery. Continued promising results in a new patient series highlight its effectiveness in oculoplastic procedures.

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Area of Science:

  • Ophthalmology
  • Plastic Surgery

Background:

  • Previous data on EnduraGen (a surgical material) for eyelid surgery was published in 2008.
  • The initial study included 69 patients and 129 eyelids.

Purpose of the Study:

  • To present updated findings on the use of EnduraGen in eyelid surgery.
  • To discuss surgical technique and procedural subtleties associated with EnduraGen.

Main Methods:

  • The authors gained experience with EnduraGen in an additional 19 patients.
  • Surgical techniques and patient outcomes were observed.

Main Results:

  • Results in the additional series of 19 patients have continued to be promising.
  • The material demonstrates ongoing efficacy in eyelid reconstructive and cosmetic procedures.

Conclusions:

  • EnduraGen remains a promising material for eyelid surgery.
  • Further discussion of surgical nuances can aid practitioners.