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[Obstructive airway diseases--emphysema. Diagnosis and therapy]
D Schött1, G H Micklefield, W T Ulmer
1Medizinische Universitätsklinik und Poliklinik, Bergmannsheil Bochum.
Summary
Whole body plethysmography reliably diagnoses airway obstruction and pulmonary emphysema, unlike spirometry. Treatment involves bronchodilators, and for bronchitis, glucocorticoids, potentially slowing emphysema progression.
Area of Science:
- Pulmonology
- Respiratory Medicine
Context:
- Spirometry is limited in diagnosing pulmonary emphysema.
- Accurate diagnosis of airway obstruction and emphysema is crucial for effective management.
Purpose:
- To compare diagnostic modalities for airway obstruction and pulmonary emphysema.
- To outline current therapeutic strategies for these conditions.
Summary:
- Whole body plethysmography offers superior qualitative and quantitative diagnosis for both airway obstruction and pulmonary emphysema compared to spirometry.
- Pharmacological management includes beta-2-sympathomimetics and theophyllines as primary bronchodilators.
- Glucocorticoids are essential for managing concurrent bronchitis, while antibiotics have limited efficacy alone.
- While pulmonary emphysema is irreversible, intensive bronchitis treatment may slow its progression.
- Causal treatment is limited to alpha-1-antitrypsin deficiency substitution therapy.
- Surgical intervention is reserved for bullous pulmonary emphysema.
Impact:
- Highlights the diagnostic superiority of whole body plethysmography.
- Provides a concise overview of current treatment guidelines for obstructive lung diseases.
- Emphasizes the importance of managing inflammatory bronchitis to potentially mitigate emphysema progression.