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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

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Neonatal erythema multiforme: a case report.

Young Joon Cho¹, Sun Young Huh, Jong Soo Hong

¹Chois Skin Clinic, Seoul, Korea.

Annals of Dermatology

|September 13, 2011

Summary

Neonatal erythema multiforme (EM) is exceptionally rare, with only three prior cases reported globally. This case highlights a Korean preterm infant experiencing EM post-vaccination, emphasizing the need for further research into its causes and management.

Keywords:

Erythema multiforme Neonate Neutropenia

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Neonatal Pial Surface Electroporation

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Published on: May 28, 2013

Area of Science:

Dermatology
Neonatology
Pediatrics

Background:

Erythema multiforme (EM) is a rare dermatological condition characterized by targetoid lesions.
Neonatal EM is exceptionally rare, with limited documented cases worldwide.
This study reports the first case of neonatal EM in Korea.

Observation:

A preterm neonate presented with widespread, targetoid erythematous patches at 36 days of age.
The infant experienced mild fever but no other systemic symptoms.
Potential triggers included hepatitis B and BCG vaccinations, alongside noted neutropenia.

Findings:

Skin biopsy confirmed findings consistent with erythema multiforme.
Intravenous methylprednisolone rapidly resolved the skin lesions.
Neutropenia persisted longer than the skin manifestations.

Implications:

This case expands the understanding of neonatal EM presentation and rarity.
The relationship between vaccination, neutropenia, and EM development requires further investigation.
Prompt treatment with corticosteroids can effectively manage neonatal EM symptoms.